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The Spirocyclic Imine from a Marine Benthic Dinoflagellate, Portimine, Is a Potent Anti-Human Immunodeficiency Virus Type 1 Therapeutic Lead Compound

In this study, we aimed to find chemicals from lower sea animals with defensive effects against human immunodeficiency virus type 1 (HIV-1). A library of marine natural products consisting of 80 compounds was screened for activity against HIV-1 infection using a luciferase-encoding HIV-1 vector. We...

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Detalles Bibliográficos
Autores principales: Izumida, Mai, Suga, Koushirou, Ishibashi, Fumito, Kubo, Yoshinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780162/
https://www.ncbi.nlm.nih.gov/pubmed/31450557
http://dx.doi.org/10.3390/md17090495