Echinochrome A Promotes Ex Vivo Expansion of Peripheral Blood-Derived CD34(+) Cells, Potentially through Downregulation of ROS Production and Activation of the Src-Lyn-p110δ Pathway

Intracellular reactive oxygen species (ROS) play an important role in the proliferation and differentiation of hematopoietic stem and progenitor cells (HSPCs). HSPCs are difficult to be expanded ex vivo while maintaining their stemness when they are exposed to oxidative damage after being released f...

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Detalles Bibliográficos
Autores principales: Park, Ga-Bin, Kim, Min-Jung, Vasileva, Elena A., Mishchenko, Natalia P., Fedoreyev, Sergey A., Stonik, Valentin A., Han, Jin, Lee, Ho Sup, Kim, Daejin, Jeong, Jee-Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780187/
https://www.ncbi.nlm.nih.gov/pubmed/31505769
http://dx.doi.org/10.3390/md17090526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780187/
https://www.ncbi.nlm.nih.gov/pubmed/31505769
http://dx.doi.org/10.3390/md17090526

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