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Inactivation of the pgmA Gene in Streptococcus mutans Significantly Decreases Biofilm-Associated Antimicrobial Tolerance

Screening of a Streptococcus mutans mutant library indicated that pgmA mutants displayed a reduced biofilm-associated tolerance toward gentamicin. The biofilms formed by the S. mutans pgmA mutant also displayed decreased tolerance towards linezolid and vancomycin compared to wild-type biofilms. On t...

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Detalles Bibliográficos
Autores principales: Nilsson, Martin, Givskov, Michael, Twetman, Svante, Tolker-Nielsen, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780209/
https://www.ncbi.nlm.nih.gov/pubmed/31484288
http://dx.doi.org/10.3390/microorganisms7090310