The Inhibitory Effect of Protamine on Platelets is Attenuated by Heparin without Inducing Thrombocytopenia in Rodents

Protamine sulfate (PS) is a polycationic protein drug obtained from the sperm of fish, and is used to reverse the anticoagulant effect of unfractionated heparin (UFH). However, the interactions between PS, UFH, and platelets are still not clear. We measured the platelet numbers and collagen-induced...

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Detalles Bibliográficos
Autores principales: Miklosz, Joanna, Kalaska, Bartlomiej, Kaminski, Kamil, Rusak, Malgorzata, Szczubialka, Krzysztof, Nowakowska, Maria, Pawlak, Dariusz, Mogielnicki, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780366/
https://www.ncbi.nlm.nih.gov/pubmed/31533230
http://dx.doi.org/10.3390/md17090539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780366/
https://www.ncbi.nlm.nih.gov/pubmed/31533230
http://dx.doi.org/10.3390/md17090539

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