The Use of Genetically Engineered Mouse Models for Studying the Function of Mutated Driver Genes in Pancreatic Cancer

Pancreatic cancer is often treatment-resistant, with the emerging standard of care, gemcitabine, affording only a few months of incrementally-deteriorating survival. Reflecting on the history of failed clinical trials, genetically engineered mouse models (GEMMs) in oncology research provides the ins...

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Detalles Bibliográficos
Autores principales: Weng, Ching-Chieh, Lin, Yu-Chun, Cheng, Kuang-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780401/
https://www.ncbi.nlm.nih.gov/pubmed/31480737
http://dx.doi.org/10.3390/jcm8091369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780401/
https://www.ncbi.nlm.nih.gov/pubmed/31480737
http://dx.doi.org/10.3390/jcm8091369

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