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Total Syntheses and Preliminary Biological Evaluation of Brominated Fascaplysin and Reticulatine Alkaloids and Their Analogues

A simple approach toward the synthesis of the marine sponge derived pigment fascaplysin was used to obtain the marine alkaloids 3-bromofascaplysin and 3,10-dibromofascaplysin. These compounds were used for first syntheses of the alkaloids 14-bromoreticulatate and 14-bromoreticulatine. Preliminary bi...

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Detalles Bibliográficos
Autores principales: Zhidkov, Maxim E., Smirnova, Polina A., Tryapkin, Oleg A., Kantemirov, Alexey V., Khudyakova, Yuliya V., Malyarenko, Olesya S., Ermakova, Svetlana P., Grigorchuk, Valeria P., Kaune, Moritz, von Amsberg, Gunhild, Dyshlovoy, Sergey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780422/
https://www.ncbi.nlm.nih.gov/pubmed/31450717
http://dx.doi.org/10.3390/md17090496