Common Variants in 22 Genes Regulate Response to Metformin Intervention in Children with Obesity: A Pharmacogenetic Study of a Randomized Controlled Trial

Metformin is a first-line oral antidiabetic agent that has shown additional effects in treating obesity and metabolic syndrome. Inter-individual variability in metformin response could be partially explained by the genetic component. Here, we aimed to test whether common genetic variants can predict...

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Detalles Bibliográficos
Autores principales: Anguita-Ruiz, Augusto, Pastor-Villaescusa, Belén, Leis, Rosaura, Bueno, Gloria, Hoyos, Raúl, Vázquez-Cobela, Rocío, Latorre-Millán, Miriam, Cañete, M. Dolores, Caballero-Villarraso, Javier, Gil, Ángel, Cañete, Ramón, Aguilera, Concepción M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780549/
https://www.ncbi.nlm.nih.gov/pubmed/31527397
http://dx.doi.org/10.3390/jcm8091471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780549/
https://www.ncbi.nlm.nih.gov/pubmed/31527397
http://dx.doi.org/10.3390/jcm8091471

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