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Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells

Renieramycin M (RM) is a KCN-stabilized tetrahydroisoquinoline purified from the blue sponge Xestospongia sp., with nanomolar IC(50)s against several cancer cell lines. Our goal is to evaluate its combination effects with doxorubicin (DOX) in estrogen receptor positive MCF-7 breast cancer cells. MCF...

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Detalles Bibliográficos
Autores principales: Tun, Jortan O., Salvador-Reyes, Lilibeth A., Velarde, Michael C., Saito, Naoki, Suwanborirux, Khanit, Concepcion, Gisela P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780817/
https://www.ncbi.nlm.nih.gov/pubmed/31527453
http://dx.doi.org/10.3390/md17090536