Diuretic Activity of a Novel Peripherally-Restricted Orally-Active Kappa Opioid Receptor Agonist

Kappa-opioid agonists (KOAs) enhance cardiac performance, as well as reduce infarct size and prevent deleterious cardiac remodeling following myocardial infarction. Additionally, KOAs promote diuresis; however, there has been limited development of KOAs as a class due to the promotion of untoward ce...

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Detalles Bibliográficos
Autores principales: Beck, Tyler C., Hapstack, Matthew A., Ghatnekar, Gautam S., Dix, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780874/
https://www.ncbi.nlm.nih.gov/pubmed/31480425
http://dx.doi.org/10.3390/medsci7090093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780874/
https://www.ncbi.nlm.nih.gov/pubmed/31480425
http://dx.doi.org/10.3390/medsci7090093

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