α-Conotoxin TxIB: A Uniquely Selective Ligand for α6/α3β2β3 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Conditioned Place Preference in Mice

α-Conotoxin TxIB is a specific antagonist of α6/α3β2β3(α6β2*) nicotinic acetylcholine receptor (nAChR) with an IC(50) of 28 nM. Previous studies have shown that α6β2* nAChRs are abundantly expressed in midbrain dopaminergic neurons and play an important role in mediating the mechanism of nicotine an...

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Detalles Bibliográficos
Autores principales: You, Shen, Li, Xiaodan, Xiong, Jian, Zhu, Xiaoyu, Zhangsun, Dongting, Zhu, Xiaopeng, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780885/
https://www.ncbi.nlm.nih.gov/pubmed/31443523
http://dx.doi.org/10.3390/md17090490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780885/
https://www.ncbi.nlm.nih.gov/pubmed/31443523
http://dx.doi.org/10.3390/md17090490

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