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MytiLec-1 Shows Glycan-Dependent Toxicity against Brine Shrimp Artemia and Induces Apoptotic Death of Ehrlich Ascites Carcinoma Cells In Vivo

MytiLec-1, a 17 kDa lectin with β-trefoil folding that was isolated from the Mediterranean mussel (Mytilus galloprovincialis) bound to the disaccharide melibiose, Galα(1,6) Glc, and the trisaccharide globotriose, Galα(1,4) Galβ(1,4) Glc. Toxicity of the lectin was found to be low with an LC(50) valu...

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Detalles Bibliográficos
Autores principales: Hasan, Imtiaj, Asaduzzaman, A.K.M., Swarna, Rubaiya Rafique, Fujii, Yuki, Ozeki, Yasuhiro, Uddin, Md. Belal, Kabir, Syed Rashel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780975/
https://www.ncbi.nlm.nih.gov/pubmed/31466257
http://dx.doi.org/10.3390/md17090502