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Human Lupus Plasma Pro-Atherogenic Effects on Cultured Macrophages Are Not Mitigated by Statin Therapy: A Mechanistic LAPS Substudy

Background and Objectives: Atherosclerotic cardiovascular disease (CVD) remains a major cause of morbidity and mortality in persons with systemic lupus erythematosus (SLE, lupus). Atherosclerosis, which involves interplay between cholesterol metabolism and cellular inflammatory pathways, is primaril...

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Detalles Bibliográficos
Autores principales: Reiss, Allison B., Arain, Hirra A., Kasselman, Lora J., Renna, Heather A., Zhen, Juan, Voloshyna, Iryna, DeLeon, Joshua, Carsons, Steven E., Petri, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780986/
https://www.ncbi.nlm.nih.gov/pubmed/31438615
http://dx.doi.org/10.3390/medicina55090514