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Embryonic FAP(+) lymphoid tissue organizer cells generate the reticular network of adult lymph nodes
The induction of adaptive immunity is dependent on the structural organization of LNs, which is in turn governed by the stromal cells that underpin LN architecture. Using a novel fate-mapping mouse model, we trace the developmental origin of mesenchymal LN stromal cells (mLNSCs) to a previously unde...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780995/ https://www.ncbi.nlm.nih.gov/pubmed/31324739 http://dx.doi.org/10.1084/jem.20181705 |