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When alpha meets beta, mast cells get hyper

The evolutionary conservation of the catalytically inactive α-tryptase gene has remained a mystery. In this issue of JEM, Le et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20190701) unveil the existence of a novel but natural tryptase, heteromeric α/β-tryptase, a critical mediator of α-trypt...

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Detalles Bibliográficos
Autores principales: Ong, Michelle Shuling, Tergaonkar, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780996/
https://www.ncbi.nlm.nih.gov/pubmed/31362981
http://dx.doi.org/10.1084/jem.20191169