When alpha meets beta, mast cells get hyper

The evolutionary conservation of the catalytically inactive α-tryptase gene has remained a mystery. In this issue of JEM, Le et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20190701) unveil the existence of a novel but natural tryptase, heteromeric α/β-tryptase, a critical mediator of α-trypt...

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Detalles Bibliográficos
Autores principales: Ong, Michelle Shuling, Tergaonkar, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780996/
https://www.ncbi.nlm.nih.gov/pubmed/31362981
http://dx.doi.org/10.1084/jem.20191169
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author Ong, Michelle Shuling
Tergaonkar, Vinay
author_facet Ong, Michelle Shuling
Tergaonkar, Vinay
author_sort Ong, Michelle Shuling
collection PubMed
description The evolutionary conservation of the catalytically inactive α-tryptase gene has remained a mystery. In this issue of JEM, Le et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20190701) unveil the existence of a novel but natural tryptase, heteromeric α/β-tryptase, a critical mediator of α-tryptase–associated diseases.
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spelling pubmed-67809962020-04-07 When alpha meets beta, mast cells get hyper Ong, Michelle Shuling Tergaonkar, Vinay J Exp Med News The evolutionary conservation of the catalytically inactive α-tryptase gene has remained a mystery. In this issue of JEM, Le et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20190701) unveil the existence of a novel but natural tryptase, heteromeric α/β-tryptase, a critical mediator of α-tryptase–associated diseases. Rockefeller University Press 2019-10-07 2019-07-30 /pmc/articles/PMC6780996/ /pubmed/31362981 http://dx.doi.org/10.1084/jem.20191169 Text en © 2019 Ong and Tergaonkar http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Ong, Michelle Shuling
Tergaonkar, Vinay
When alpha meets beta, mast cells get hyper
title When alpha meets beta, mast cells get hyper
title_full When alpha meets beta, mast cells get hyper
title_fullStr When alpha meets beta, mast cells get hyper
title_full_unstemmed When alpha meets beta, mast cells get hyper
title_short When alpha meets beta, mast cells get hyper
title_sort when alpha meets beta, mast cells get hyper
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780996/
https://www.ncbi.nlm.nih.gov/pubmed/31362981
http://dx.doi.org/10.1084/jem.20191169
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