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Anti-idiotypic antibodies elicit anti-HIV-1–specific B cell responses

Human anti-HIV-1 broadly neutralizing antibodies (bNAbs) protect against infection in animal models. However, bNAbs have not been elicited by vaccination in diverse wild-type animals or humans, in part because B cells expressing the precursors of these antibodies do not recognize most HIV-1 envelope...

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Detalles Bibliográficos
Autores principales: Dosenovic, Pia, Pettersson, Anna-Klara, Wall, Abigail, Thientosapol, Eddy S., Feng, Junli, Weidle, Connor, Bhullar, Komal, Kara, Ervin E., Hartweger, Harald, Pai, Joy A., Gray, Matthew D., Parks, K. Rachael, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, Nussenzweig, Michel C., McGuire, Andrew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780999/
https://www.ncbi.nlm.nih.gov/pubmed/31345931
http://dx.doi.org/10.1084/jem.20190446