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Anti-idiotypic antibodies elicit anti-HIV-1–specific B cell responses
Human anti-HIV-1 broadly neutralizing antibodies (bNAbs) protect against infection in animal models. However, bNAbs have not been elicited by vaccination in diverse wild-type animals or humans, in part because B cells expressing the precursors of these antibodies do not recognize most HIV-1 envelope...
Autores principales: | Dosenovic, Pia, Pettersson, Anna-Klara, Wall, Abigail, Thientosapol, Eddy S., Feng, Junli, Weidle, Connor, Bhullar, Komal, Kara, Ervin E., Hartweger, Harald, Pai, Joy A., Gray, Matthew D., Parks, K. Rachael, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, Nussenzweig, Michel C., McGuire, Andrew T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780999/ https://www.ncbi.nlm.nih.gov/pubmed/31345931 http://dx.doi.org/10.1084/jem.20190446 |
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