CSF-1 controls cerebellar microglia and is required for motor function and social interaction

Microglia, the brain resident macrophages, critically shape forebrain neuronal circuits. However, their precise function in the cerebellum is unknown. Here we show that human and mouse cerebellar microglia express a unique molecular program distinct from forebrain microglia. Cerebellar microglial id...

Descripción completa

Detalles Bibliográficos
Autores principales: Kana, Veronika, Desland, Fiona A., Casanova-Acebes, Maria, Ayata, Pinar, Badimon, Ana, Nabel, Elisa, Yamamuro, Kazuhiko, Sneeboer, Marjolein, Tan, I-Li, Flanigan, Meghan E., Rose, Samuel A., Chang, Christie, Leader, Andrew, Le Bourhis, Hortense, Sweet, Eric S., Tung, Navpreet, Wroblewska, Aleksandra, Lavin, Yonit, See, Peter, Baccarini, Alessia, Ginhoux, Florent, Chitu, Violeta, Stanley, E. Richard, Russo, Scott J., Yue, Zhenyu, Brown, Brian D., Joyner, Alexandra L., De Witte, Lotje D., Morishita, Hirofumi, Schaefer, Anne, Merad, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781012/
https://www.ncbi.nlm.nih.gov/pubmed/31350310
http://dx.doi.org/10.1084/jem.20182037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781012/
https://www.ncbi.nlm.nih.gov/pubmed/31350310
http://dx.doi.org/10.1084/jem.20182037

Ejemplares similares