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Gold@Silica Nanoparticles Functionalized with Oligonucleotides: A Prominent Tool for the Detection of the Methylated Reprimo Gene in Gastric Cancer by Dynamic Light Scattering

Reprimo (RPRM) is a tumor suppressor gene involved in the development of gastric cancer. Hypermethylation of the RPRM promoter region has been found in tumor tissue and plasma samples from patients with gastric cancer. These findings suggest that circulating methylated DNA of RPRM could be a candida...

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Detalles Bibliográficos
Autores principales: Marchant, María José, Guzmán, Leda, Corvalán, Alejandro H., Kogan, Marcelo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781027/
https://www.ncbi.nlm.nih.gov/pubmed/31540371
http://dx.doi.org/10.3390/nano9091333