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Discovery of Bioactive Indole-Diketopiperazines from the Marine-Derived Fungus Penicillium brasilianum Aided by Genomic Information

Identification and analysis of the whole genome of the marine-derived fungus Penicillium brasilianum HBU-136 revealed the presence of an interesting biosynthetic gene cluster (BGC) for non-ribosomal peptide synthetases (NRPS), highly homologous to the BGCs of indole-diketopiperazine derivatives. Wit...

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Detalles Bibliográficos
Autores principales: Zhang, Ya-Hui, Geng, Ce, Zhang, Xing-Wang, Zhu, Hua-Jie, Shao, Chang-Lun, Cao, Fei, Wang, Chang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781160/
https://www.ncbi.nlm.nih.gov/pubmed/31480589
http://dx.doi.org/10.3390/md17090514