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Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer

Background: This study evaluated the antineoplastic and immunostimulatory effects of inhaled (IH) submicron particle paclitaxel (NanoPac(®)) in an orthotopic non-small cell lung cancer rodent model. Methods: Male nude rats were whole body irradiated, intratracheally instilled with Calu-3 cancer cell...

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Detalles Bibliográficos
Autores principales: Verco, James, Johnston, William, Frost, Michael, Baltezor, Michael, Kuehl, Philip J., Lopez, Anita, Gigliotti, Andrew, Belinsky, Steven A., Wolff, Ronald, diZerega, Gere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781259/
https://www.ncbi.nlm.nih.gov/pubmed/31347939
http://dx.doi.org/10.1089/jamp.2018.1517