Inclusion Complexes of Melphalan with Gemini-Conjugated β-Cyclodextrin: Physicochemical Properties and Chemotherapeutic Efficacy in In-Vitro Tumor Models

β-cyclodextrin (βCD) has been widely explored as an excipient for pharmaceuticals and nutraceuticals as it forms stable host–guest inclusion complexes and enhances the solubility of poorly soluble active agents. To enhance intracellular drug delivery, βCD was chemically conjugated to an 18-carbon ch...

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Detalles Bibliográficos
Autores principales: Mohammed-Saeid, Waleed, Karoyo, Abdalla H, Verrall, Ronald E, Wilson, Lee D, Badea, Ildiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781286/
https://www.ncbi.nlm.nih.gov/pubmed/31443452
http://dx.doi.org/10.3390/pharmaceutics11090427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781286/
https://www.ncbi.nlm.nih.gov/pubmed/31443452
http://dx.doi.org/10.3390/pharmaceutics11090427

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