Impact of GSTA1 Polymorphisms on Busulfan Oral Clearance in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation

Background: Busulfan pharmacokinetics exhibit large inter-subject variability. Our objective was to evaluate the influence of glutathione S-transferase A1 (GSTA1) gene variants on busulfan oral clearance (CLo) in a population of patients undergoing hematopoietic stem cell transplantation. Methods: T...

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Detalles Bibliográficos
Autores principales: Michaud, Veronique, Tran, My, Pronovost, Benoit, Bouchard, Philippe, Bilodeau, Sarah, Alain, Karine, Vadnais, Barbara, Franco, Martin, Bélanger, François, Turgeon, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781287/
https://www.ncbi.nlm.nih.gov/pubmed/31480560
http://dx.doi.org/10.3390/pharmaceutics11090440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781287/
https://www.ncbi.nlm.nih.gov/pubmed/31480560
http://dx.doi.org/10.3390/pharmaceutics11090440

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