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PVP-H(2)O(2) Complex as a New Stressor for the Accelerated Oxidation Study of Pharmaceutical Solids

Reactive impurities, such as hydrogen peroxide in excipients, raise a great concern over the chemical stability of pharmaceutical products. Traditional screening methods of spiking impurities into solid drug-excipient mixtures oversimplify the micro-environment and the physical state of such impurit...

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Detalles Bibliográficos
Autores principales: Modhave, Dattatray, Barrios, Brenda, Paudel, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781290/
https://www.ncbi.nlm.nih.gov/pubmed/31484442
http://dx.doi.org/10.3390/pharmaceutics11090457