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PVP-H(2)O(2) Complex as a New Stressor for the Accelerated Oxidation Study of Pharmaceutical Solids
Reactive impurities, such as hydrogen peroxide in excipients, raise a great concern over the chemical stability of pharmaceutical products. Traditional screening methods of spiking impurities into solid drug-excipient mixtures oversimplify the micro-environment and the physical state of such impurit...
Autores principales: | Modhave, Dattatray, Barrios, Brenda, Paudel, Amrit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781290/ https://www.ncbi.nlm.nih.gov/pubmed/31484442 http://dx.doi.org/10.3390/pharmaceutics11090457 |
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