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A Valid Bisphosphonate Modified Calcium Phosphate-Based Gene Delivery System: Increased Stability and Enhanced Transfection Efficiency In Vitro and In Vivo

Calcium phosphate (CaP) nanoparticles, as a promising vehicle for gene delivery, have been widely used owing to their biocompatibility, biodegradability and adsorptive capacity for nucleic acids. Unfortunately, their utility in vivo has been profoundly restricted due to numerous technical barriers s...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Li, Ji, Chen, Dawei, Hu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781291/
https://www.ncbi.nlm.nih.gov/pubmed/31514452
http://dx.doi.org/10.3390/pharmaceutics11090468