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Development and Evaluation of Multifunctional Poly(Lactic-co-glycolic acid) Nanoparticles Embedded in Carboxymethyl β-Glucan Porous Microcapsules as a Novel Drug Delivery System for Gefitinib

In this study, a new kind of folic acid (FA)-conjugated and chitosan (CS)-coated poloxamer 407 (P407)/poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs), FCPP NPs, were prepared, and further micro-encapsulated by carboxymethyl β-glucan microcapsules (MCs) to produce a multifunctional system of...

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Detalles Bibliográficos
Autores principales: Li, Xiaonan, Wang, Jinglei, Li, Shang, Liu, Zhaorong, Zheng, Zhiru, Zhang, Yanzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781315/
https://www.ncbi.nlm.nih.gov/pubmed/31547272
http://dx.doi.org/10.3390/pharmaceutics11090469