Uptake of a fluorescently tagged chloroquine analogue is reduced in CQ-resistant compared to CQ-sensitive Plasmodium falciparum parasites

BACKGROUND: Chloroquine (CQ) was the drug of choice for decades in the treatment of falciparum malaria until resistance emerged. CQ is suggested to accumulate in the parasite’s digestive vacuole (DV), where it unfolds its anti-malarial properties. Discrepancies of CQ accumulation in CQ-sensitive (CQ...

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Detalles Bibliográficos
Autores principales: Reiling, Sarah J., Rohrbach, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781371/
https://www.ncbi.nlm.nih.gov/pubmed/31590674
http://dx.doi.org/10.1186/s12936-019-2980-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781371/
https://www.ncbi.nlm.nih.gov/pubmed/31590674
http://dx.doi.org/10.1186/s12936-019-2980-y

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