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Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

Ischemic stroke causes blood–brain barrier (BBB) breakdown due to significant damage to the integrity of BBB components. Recent studies have highlighted the importance of pericytes in the repair process of BBB functions triggered by PDGFRβ up-regulation. Here, we show that perlecan, a major heparan...

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Detalles Bibliográficos
Autores principales: Nakamura, Kuniyuki, Ikeuchi, Tomoko, Nara, Kazuki, Rhodes, Craig S., Zhang, Peipei, Chiba, Yuta, Kazuno, Saiko, Miura, Yoshiki, Ago, Tetsuro, Arikawa-Hirasawa, Eri, Mukouyama, Yoh-suke, Yamada, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781430/
https://www.ncbi.nlm.nih.gov/pubmed/31541017
http://dx.doi.org/10.1083/jcb.201807178