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Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity

Tight junctions (TJs) establish the epithelial barrier and are thought to form a membrane fence to regulate epithelial polarity, although the roles of TJs in epithelial polarity remain controversial. Claudins constitute TJ strands in conjunction with the cytoplasmic scaffolds ZO-1 and ZO-2 and play...

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Detalles Bibliográficos
Autores principales: Otani, Tetsuhisa, Nguyen, Thanh Phuong, Tokuda, Shinsaku, Sugihara, Kei, Sugawara, Taichi, Furuse, Kyoko, Miura, Takashi, Ebnet, Klaus, Furuse, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781433/
https://www.ncbi.nlm.nih.gov/pubmed/31467165
http://dx.doi.org/10.1083/jcb.201812157