The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

Focal adhesion (FA) turnover depends on microtubules and actin. Microtubule ends are captured at FAs, where they induce rapid FA disassembly. However, actin’s roles are less clear. Here, we use polarization-resolved microscopy, FRAP, live cell imaging, and a mutant of Adenomatous polyposis coli (APC...

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Detalles Bibliográficos
Autores principales: Juanes, M. Angeles, Isnardon, Daniel, Badache, Ali, Brasselet, Sophie, Mavrakis, Manos, Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781439/
https://www.ncbi.nlm.nih.gov/pubmed/31471457
http://dx.doi.org/10.1083/jcb.201904165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781439/
https://www.ncbi.nlm.nih.gov/pubmed/31471457
http://dx.doi.org/10.1083/jcb.201904165

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