Hair follicle regeneration suppresses Ras-driven oncogenic growth

Mutations associated with tumor development in certain tissues can be nontumorigenic in others, yet the mechanisms underlying these different outcomes remains poorly understood. To address this, we targeted an activating Hras mutation to hair follicle stem cells and discovered that Hras mutant cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Pineda, Cristiana M., Gonzalez, David G., Matte-Martone, Catherine, Boucher, Jonathan, Lathrop, Elizabeth, Gallini, Sara, Fons, Nathan R., Xin, Tianchi, Tai, Karen, Marsh, Edward, Nguyen, Don X., Suozzi, Kathleen C., Beronja, Slobodan, Greco, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781447/
https://www.ncbi.nlm.nih.gov/pubmed/31488583
http://dx.doi.org/10.1083/jcb.201907178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781447/
https://www.ncbi.nlm.nih.gov/pubmed/31488583
http://dx.doi.org/10.1083/jcb.201907178

Ejemplares similares