A kindlin-3–leupaxin–paxillin signaling pathway regulates podosome stability

Binding of kindlins to integrins is required for integrin activation, stable ligand binding, and subsequent intracellular signaling. How hematopoietic kindlin-3 contributes to the assembly and stability of the adhesion complex is not known. Here we report that kindlin-3 recruits leupaxin into podoso...

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Detalles Bibliográficos
Autores principales: Klapproth, Sarah, Bromberger, Thomas, Türk, Clara, Krüger, Marcus, Moser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781449/
https://www.ncbi.nlm.nih.gov/pubmed/31537712
http://dx.doi.org/10.1083/jcb.201903109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781449/
https://www.ncbi.nlm.nih.gov/pubmed/31537712
http://dx.doi.org/10.1083/jcb.201903109

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