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A kindlin-3–leupaxin–paxillin signaling pathway regulates podosome stability

Binding of kindlins to integrins is required for integrin activation, stable ligand binding, and subsequent intracellular signaling. How hematopoietic kindlin-3 contributes to the assembly and stability of the adhesion complex is not known. Here we report that kindlin-3 recruits leupaxin into podoso...

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Detalles Bibliográficos
Autores principales:	Klapproth, Sarah, Bromberger, Thomas, Türk, Clara, Krüger, Marcus, Moser, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781449/ https://www.ncbi.nlm.nih.gov/pubmed/31537712 http://dx.doi.org/10.1083/jcb.201903109

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