Downregulation of ABCA1 and ABCG1 transporters by simvastatin in cholangiocarcinoma cells

Disturbances in cholesterol homeostasis of the bile duct epithelium, including transport interruption and the hyperaccumulation of intracellular cholesterol can lead to the initiation and progression of cholangiocarcinoma (CCA). Statins, which are lipid-lowering drugs, have been previously documente...

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Detalles Bibliográficos
Autores principales: Seeree, Pattaya, Janvilisri, Tavan, Kangsamaksin, Thaned, Tohtong, Rutaiwan, Kumkate, Supeecha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781495/
https://www.ncbi.nlm.nih.gov/pubmed/31612028
http://dx.doi.org/10.3892/ol.2019.10874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781495/
https://www.ncbi.nlm.nih.gov/pubmed/31612028
http://dx.doi.org/10.3892/ol.2019.10874

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