Cargando…

Downregulation of ABCA1 and ABCG1 transporters by simvastatin in cholangiocarcinoma cells

Disturbances in cholesterol homeostasis of the bile duct epithelium, including transport interruption and the hyperaccumulation of intracellular cholesterol can lead to the initiation and progression of cholangiocarcinoma (CCA). Statins, which are lipid-lowering drugs, have been previously documente...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seeree, Pattaya, Janvilisri, Tavan, Kangsamaksin, Thaned, Tohtong, Rutaiwan, Kumkate, Supeecha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781495/ https://www.ncbi.nlm.nih.gov/pubmed/31612028 http://dx.doi.org/10.3892/ol.2019.10874

Ejemplares similares

An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma
por: Seeree, Pattaya, et al.
Publicado: (2015)

Dysregulation of microRNA in cholangiocarcinoma identified through a meta-analysis of microRNA profiling
por: Likhitrattanapisal, Somsak, et al.
Publicado: (2020)

Co-Clinical Trials: An Innovative Drug Development Platform for Cholangiocarcinoma
por: Balasubramanian, Brinda, et al.
Publicado: (2021)

Andrographolide Inhibits Cholangiocarcinoma Cell Migration by Down-Regulation of Claudin-1 via the p-38 Signaling Pathway
por: Pearngam, Phorutai, et al.
Publicado: (2019)

Distinct cholangiocarcinoma cell migration in 2D monolayer and 3D spheroid culture based on galectin-3 expression and localization
por: Sukphokkit, Siriwat, et al.
Publicado: (2023)

Asiatic Acid Inhibits Nasopharyngeal Carcinoma Cell Viability and Migration via Suppressing STAT3 and Claudin-1
por: Pantia, Supitchaya, et al.
Publicado: (2023)

Novel Serum Biomarkers to Differentiate Cholangiocarcinoma from Benign Biliary Tract Diseases Using a Proteomic Approach
por: Janvilisri, Tavan, et al.
Publicado: (2015)

RTK25: A Comprehensive Molecular Profiling Strategy in Cholangiocarcinoma Using an Integrated Bioinformatics Approach
por: Balasubramanian, Brinda, et al.
Publicado: (2021)

Baicalein Inhibits Metastatic Phenotypes in Nasopharyngeal Carcinoma Cells via a Focal Adhesion Protein Integrin β8
por: Kiatwuthinon, Pichamon, et al.
Publicado: (2021)

Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells
por: Boonsri, Boonyakorn, et al.
Publicado: (2021)

Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth in mice via downregulation of tumor necrosis factor-α
por: Kangsamaksin, Thaned, et al.
Publicado: (2017)

CD24 induces the invasion of cholangiocarcinoma cells by upregulating CXCR4 and increasing the phosphorylation of ERK1/2
por: LEELAWAT, KAWIN, et al.
Publicado: (2013)

Role of mTOR inhibitor in cholangiocarcinoma cell progression
por: MOOLTHIYA, PENPAK, et al.
Publicado: (2014)

Targeting FGFRs Using PD173074 as a Novel Therapeutic Strategy in Cholangiocarcinoma
por: Balasubramanian, Brinda, et al.
Publicado: (2023)

Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach
por: Venkatraman, Simran, et al.
Publicado: (2022)

Cholesterol Transporters ABCA1 and ABCG1 Gene Expression in Peripheral Blood Mononuclear Cells in Patients with Metabolic Syndrome
por: Tavoosi, Zahra, et al.
Publicado: (2015)

Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
por: Akara-amornthum, Perawatt, et al.
Publicado: (2020)

Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP
por: Hussain, Syed Saad, et al.
Publicado: (2018)

DNA origami applications in cancer therapy
por: Udomprasert, Anuttara, et al.
Publicado: (2017)

Genomic Variants and Multilevel Regulation of ABCA1, ABCG1, and SCARB1 Expression in Atherogenesis
por: Rozhkova, Alexandra V., et al.
Publicado: (2021)

ABCA1, ABCG1, and ABCG4 Are Distributed to Distinct Membrane Meso-Domains and Disturb Detergent-Resistant Domains on the Plasma Membrane
por: Sano, Osamu, et al.
Publicado: (2014)

Gadd45β silencing impaired viability and metastatic phenotypes in cholangiocarcinoma cells by modulating the EMT pathway
por: Myint, Kyaw Zwar, et al.
Publicado: (2018)

Tetrahedral DNA nanostructures as drug delivery and bioimaging platforms in cancer therapy
por: Duangrat, Ratchanee, et al.
Publicado: (2020)

In Silico Target Identification of Galangin, as an Herbal Flavonoid against Cholangiocarcinoma
por: Balasubramanian, Brinda, et al.
Publicado: (2022)

Expression of LXR-β, ABCA1 and ABCG1 in human triple-negative breast cancer tissues
por: Pan, Hailing, et al.
Publicado: (2019)

ABCA1 and ABCG1 DNA methylation in epicardial adipose tissue of patients with coronary artery disease
por: Miroshnikova, Valentina V., et al.
Publicado: (2021)

Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma
por: Lomphithak, Thanpisit, et al.
Publicado: (2020)

ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines
por: Sporstøl, Marita, et al.
Publicado: (2007)

Mangiferin promotes macrophage cholesterol efflux and protects against atherosclerosis by augmenting the expression of ABCA1 and ABCG1
por: Ren, Kun, et al.
Publicado: (2019)

Rosmarinic Acid Increases Macrophage Cholesterol Efflux through Regulation of ABCA1 and ABCG1 in Different Mechanisms
por: Nyandwi, Jean-Baptiste, et al.
Publicado: (2021)

Tetramethylpyrazine and Paeoniflorin Synergistically Attenuate Cholesterol Efflux in Macrophage Cells via Enhancing ABCA1 and ABCG1 Expression
por: Mei, Jun, et al.
Publicado: (2022)

Combined Effects of Fludarabine and Interferon Alpha on Autophagy Regulation Define the Phase of Cell Survival and Promotes Responses in LLC-MK2 and K562 Cells
por: Bowornruangrit, Pathompong, et al.
Publicado: (2022)

Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability
por: Pajvani, Utpal B., et al.
Publicado: (2013)

Advanced Glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1
por: Iborra, Rodrigo T, et al.
Publicado: (2011)

Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis
por: Adlakha, Y K, et al.
Publicado: (2013)

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration
por: Storti, Federica, et al.
Publicado: (2019)

Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired β-Cell Function
por: Kruit, Janine K., et al.
Publicado: (2012)

Omics-Based Identification of Biomarkers for Nasopharyngeal Carcinoma
por: Janvilisri, Tavan
Publicado: (2015)

ABCG5 and ABCG8 Are Involved in Vitamin K Transport
por: Matsuo, Michinori, et al.
Publicado: (2023)

Cellular Localization and Trafficking of the Human ABCG1 Transporter
por: Neufeld, Edward B., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_d3mmkecpijjc6c124b097c72jp