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Different responses to anti-programmed cell death protein 1 (PD-1) immunotherapy in a patient with Lynch syndrome and metachronous urothelial and colon cancer: A case report

Lynch syndrome (LS), as a result of the germline mutations in DNA mismatch repair genes, is characterized by the increased risk of endometrium, colon, and urinary tract cancer. Individuals with this disorder may occasionally have multiple primary carcinomas. Regardless of tumor type, pembrolizumab w...

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Detalles Bibliográficos
Autores principales: Feng, Yu, Cao, Yufeng, Yuan, Mingming, Chen, Rongrong, Ji, Xue, Hu, Xingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781514/
https://www.ncbi.nlm.nih.gov/pubmed/31612019
http://dx.doi.org/10.3892/ol.2019.10909