Understanding and Kinetic Modeling of Complex Degradation Pathways in the Solid Dosage Form: The Case of Saxagliptin

Drug substance degradation kinetics in solid dosage forms is rarely mechanistically modeled due to several potential micro-environmental and manufacturing related effects that need to be integrated into rate laws. The aim of our work was to construct a model capable of predicting individual degradat...

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Detalles Bibliográficos
Autores principales: Robnik, Blaž, Likozar, Blaž, Wang, Baifan, Stanić Ljubin, Tijana, Časar, Zdenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781548/
https://www.ncbi.nlm.nih.gov/pubmed/31480788
http://dx.doi.org/10.3390/pharmaceutics11090452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781548/
https://www.ncbi.nlm.nih.gov/pubmed/31480788
http://dx.doi.org/10.3390/pharmaceutics11090452

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