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An Injectable Click-Crosslinked Hydrogel that Prolongs Dexamethasone Release from Dexamethasone-Loaded Microspheres

Our purpose was to test whether a preparation of injectable formulations of dexamethasone (Dex)-loaded microspheres (Dex-Ms) mixed with click-crosslinked hyaluronic acid (Cx-HA) (or Pluronic (PH) for comparison) prolongs therapeutic levels of released Dex. Dex-Ms were prepared using a monoaxial-nozz...

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Detalles Bibliográficos
Autores principales: Heo, Ji Yeon, Noh, Jung Hyun, Park, Seung Hun, Ji, Yun Bae, Ju, Hyeon Jin, Kim, Da Yeon, Lee, Bong, Kim, Moon Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781549/
https://www.ncbi.nlm.nih.gov/pubmed/31480552
http://dx.doi.org/10.3390/pharmaceutics11090438