A-1210477, a selective MCL-1 inhibitor, overcomes ABT-737 resistance in AML

Acute myeloid leukemia (AML) is one of the most common hematological malignancies. It is difficult to treat since it easily develops resistance to therapeutic drugs. Myeloid cell leukemia 1 (MCL-1), BCL-2 and BCL-XL, which belong to the anti-apoptotic group of proteins in the BCL-2 family, are overe...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Hao, Siguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781566/
https://www.ncbi.nlm.nih.gov/pubmed/31612056
http://dx.doi.org/10.3892/ol.2019.10891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781566/
https://www.ncbi.nlm.nih.gov/pubmed/31612056
http://dx.doi.org/10.3892/ol.2019.10891

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