Akt/mTOR-Mediated Autophagy Confers Resistance To BET Inhibitor JQ1 In Ovarian Cancer

BACKGROUND: Bromodomain and extra-terminal domain inhibitors like JQ1 have proved to be promising epigenetic agents for the treatment of malignant ovarian carcinoma. However, the resistance of ovarian cancer cells to BET inhibitors has not been elucidated. In this study, we investigated the potentia...

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Detalles Bibliográficos
Autores principales: Luan, Wenqing, Pang, Yingxin, Li, Rui, Wei, Xuan, Jiao, Xiaoxiao, Shi, Juanjuan, Yu, Jiangtao, Mao, Hongluan, Liu, Peishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781612/
https://www.ncbi.nlm.nih.gov/pubmed/31632060
http://dx.doi.org/10.2147/OTT.S220267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781612/
https://www.ncbi.nlm.nih.gov/pubmed/31632060
http://dx.doi.org/10.2147/OTT.S220267

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