Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis

Poor response and resistance to cisplatin (DDP)-based chemotherapy frequently leads to treatment failure in advanced non-small cell lung cancer (NSCLC). The underlying molecular mechanism is extremely complex and currently remains unclear. The overexpression of cancerous inhibitor of protein phospha...

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Detalles Bibliográficos
Autores principales: Feng, Feifei, Cheng, Peng, Wang, Chaochao, Wang, Yongbin, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781722/
https://www.ncbi.nlm.nih.gov/pubmed/31612051
http://dx.doi.org/10.3892/ol.2019.10895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781722/
https://www.ncbi.nlm.nih.gov/pubmed/31612051
http://dx.doi.org/10.3892/ol.2019.10895

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