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Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis

Poor response and resistance to cisplatin (DDP)-based chemotherapy frequently leads to treatment failure in advanced non-small cell lung cancer (NSCLC). The underlying molecular mechanism is extremely complex and currently remains unclear. The overexpression of cancerous inhibitor of protein phospha...

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Detalles Bibliográficos
Autores principales:	Feng, Feifei, Cheng, Peng, Wang, Chaochao, Wang, Yongbin, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781722/ https://www.ncbi.nlm.nih.gov/pubmed/31612051 http://dx.doi.org/10.3892/ol.2019.10895

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