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IFN Regulatory Factor 4 Controls Post-ischemic Inflammation and Prevents Chronic Kidney Disease

Ischemia reperfusion injury (IRI) of the kidney results in interferon regulatory factor 4 (IRF4)–mediated counter-regulation of the acute inflammatory response. Beyond that, IRF4 exerts important functions in controlling the cytokine milieu, T-cell differentiation, and macrophage polarization. The l...

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Detalles Bibliográficos
Autores principales: Lorenz, Georg, Moschovaki-Filippidou, Foteini, Würf, Vivian, Metzger, Philipp, Steiger, Stefanie, Batz, Falk, Carbajo-Lozoya, Javier, Koziel, Joanna, Schnurr, Max, Cohen, Clemens D., Schmaderer, Christoph, Anders, Hans-Joachim, Lindenmeyer, Maja, Lech, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781770/
https://www.ncbi.nlm.nih.gov/pubmed/31632388
http://dx.doi.org/10.3389/fimmu.2019.02162