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Platelet-derived growth factor-BB promotes proliferation and migration of retinal microvascular pericytes by up-regulating the expression of C-X-C chemokine receptor types 4

Stromal cell-derived growth factor (SDF)-1α acts as a ligand to C-X-C chemokine receptors 4 (CXCR4) and 7 (CXCR7), which are involved in the formation of choroidal neovascularization. Previous studies have demonstrated crosstalk between the platelet-derived growth factor (PDGF)-BB/PDGF receptor (PDG...

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Detalles Bibliográficos
Autores principales: Xiang, Dan-Ni, Feng, Yi-Fan, Wang, Jing, Zhang, Xi, Shen, Jing-Jing, Zou, Rong, Yuan, Yuan-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781788/
https://www.ncbi.nlm.nih.gov/pubmed/31611940
http://dx.doi.org/10.3892/etm.2019.8016