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Hepatic expression of programmed death-1 (PD-1) and its ligand, PD-L1, in children with autoimmune hepatitis: relation to treatment response

AIM OF THE STUDY: Autoimmune hepatitis (AIH) is characterized histologically by aggressive inflammation with interface hepatitis and prominent lymphoplasmacytic infiltration. Programmed death-1 (PD-1) is expressed on activated lymphocytes. Engagement of PD-1 by its ligand PD-L1 leads to cell apoptos...

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Detalles Bibliográficos
Autores principales: Agina, Hala A., Ehsan, Nermine A., Abd-Elaziz, Taghreed A., Abd-Elfatah, Ghada A., Said, Eman M., Sira, Mostafa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781821/
https://www.ncbi.nlm.nih.gov/pubmed/31598564
http://dx.doi.org/10.5114/ceh.2019.87642