Saccharomyces cerevisiae Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding

Two common features of centromeres are their transcription into noncoding centromere RNAs (cen-RNAs) and their assembly into nucleosomes that contain a centromere-specific histone H3 (cenH3). Here, we show that Saccharomyces cerevisiae cen-RNA was present in low amounts in wild-type (WT) cells, and...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Fu, Pohl, Thomas J., Chan, Angela, Slocum, Joshua S., Zakian, Virginia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781895/
https://www.ncbi.nlm.nih.gov/pubmed/31391265
http://dx.doi.org/10.1534/genetics.119.302528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781895/
https://www.ncbi.nlm.nih.gov/pubmed/31391265
http://dx.doi.org/10.1534/genetics.119.302528

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