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A novel chalcone derivative exerts anti-inflammatory and anti-oxidant effects after acute lung injury

We explored the effects of compound 33, a synthetic chalcone derivative with antioxidant activity, on lipopolysaccharide (LPS)-induced acute lung injury (ALI). Compound 33, dexamethasone or vehicle was administered intragastrically to mice 6 h before intratracheal instillation of LPS. After 24 h, th...

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Detalles Bibliográficos
Autores principales: Lin, Yuting, Zhang, Man, Lu, Qingdi, Xie, Jingwen, Wu, Jianzhang, Chen, Chengshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781971/
https://www.ncbi.nlm.nih.gov/pubmed/31553308
http://dx.doi.org/10.18632/aging.102288