PRL-3 exerts oncogenic functions in myeloid leukemia cells via aberrant dephosphorylation of stathmin and activation of STAT3 signaling

PRL-3, an oncogenic dual-specificity phosphatase, is overexpressed in 50% of acute myeloid leukemia patients. Stathmin has been identified as a downstream target of PRL-3 in colorectal cancer. However, the correlation between PRL-3 and stathmin in myeloid leukemia is unclear. In this study, we revea...

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Detalles Bibliográficos
Autores principales: Xu, Jianping, Wu, Wei, Tang, Yao, Lin, Yanfeng, Xue, Yan, Hu, Jianda, Lin, Donghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781976/
https://www.ncbi.nlm.nih.gov/pubmed/31546234
http://dx.doi.org/10.18632/aging.102290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781976/
https://www.ncbi.nlm.nih.gov/pubmed/31546234
http://dx.doi.org/10.18632/aging.102290

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