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Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death

LncRNA-XIST participated in the regulation of Non-small cell lung cancer (NSCLC) progression, but the underlying mechanisms are still unclear. This study showed that LncRNA-XIST aberrantly overexpressed in either NSCLC tissues or cell lines comparing to their paired control groups. Knock-down of Lnc...

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Detalles Bibliográficos
Autores principales: Liu, Jinglei, Yao, Lei, Zhang, Mingyan, Jiang, Ji, Yang, Maopeng, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781979/
https://www.ncbi.nlm.nih.gov/pubmed/31553952
http://dx.doi.org/10.18632/aging.102291